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UCF Health is conducting three clinical trials in its dermatology department. Information on each is posted below.
Disease: Raynaud’s Phenomenon
Study Title: The Effect of Abobotulinum Toxin A on the Symptoms of Raynaud’s Phenomenon, a Double-Blind Randomized Placebo-Controlled Trial
UCF Health is conducting a study to examine the effectiveness of abobotulinum toxin A as a treatment for Raynaud’s phenomenon. Participants must have Raynaud’s phenomenon in both hands, be at least 18 years of age, and must have health insurance. You cannot be in this study if: (1) you are allergic to abobotulinum toxin A or its components, (2) you have a diagnosis of myasthenia gravis; (3) you are unable to read and speak English, (4) you are pregnant or breastfeeding, (5) you have previously received botulinum toxin vaccine, (6) you have previously undergone upper extremity vascular surgery, (7) you have previously received abobotulinum toxin A treatment in either hand in the past 6 months, (8) you are a current smoker or quit in the past 12 months, or (9) you are a prisoner. If you are female, you may need to provide a urine sample for a pregnancy test to determine if you are eligible to participate in this research study. If you are eligible and agree to participate, you will receive injections of abobotulinum toxin A into one hand and a normal saline solution into the other. The study will take place at the UCF Health clinic on Tavistock Lakes Blvd. and will require five total visits to the clinic in addition to filling out a paper or online surveys. A date and time will be arranged with you. You will receive the study treatment for your Raynaud’s phenomenon at no cost. If you are interested in participating in this study or would like more information, please contact Dr. David Weinstein (david.weinstein@ucf.edu) or Amelia Winter (arwinter@knights.ucf.edu).
Disease: Calcinosis Cutis
Study Title: A Comparative Study of the Efficacy of Intralesional Sodium Thiosulfate Versus Intralesional Normal Saline for the Treatment of Dystrophic and Idiopathic Calcinosis Cutis, A Double-Blind Randomized Placebo-Controlled Trial
UCF Health is conducting a study to assess the efficacy of sodium thiosulfate for the treatment of calcinosis cutis. Participants must have calcinosis cutis, be least 18 years of age, and must have health insurance. You cannot be in this study if: (1) you are allergic to sodium thiosulfate or its components, (2) you are unable to read and speak English, (4) you are pregnant or breastfeeding, or (5) you are a prisoner. If you are female, you may need to provide a urine sample for a pregnancy test to determine if you are eligible to participate in this research study. If you are eligible and agree to participate, you will receive an injection of sodium thiosulfate and an injection of normal saline once a month for three months with a fourth follow-up appointment. The study will take place at the UCF Health clinic on Tavistock Lakes Blvd. and will require four total visits to the clinic. A date and time will be arranged with you. You will receive the treatment for your calcinosis cutis free of charge. If you are interested in participating in this study or want more information, please contact Dr. David Weinstein (david.weinstein@ucf.edu) or Adam Foley (adamfoley7@knights.ucf.edu).
Disease: Cutaneous Lupus Erythematosus
Study Title: A Comparative Study of the Efficacy of 532nm Laser and 1064 nm laser as Adjuncts to Topical Corticosteroids in the Treatment of Cutaneous Lupus Erythematosus Versus Topical Corticosteroids Alone
UCF Health is conducting a study to examine the effectiveness of a laser as treatment for cutaneous lupus erythematosus. Participants must have cutaneous lupus lesions, be at least 18 years of age, and cannot be pregnant. If you are female, you may need to provide a urine sample for a pregnancy test to determine if you are eligible to participate in this research study. If you are eligible and agree to participate, you will receive a cream to apply to your cutaneous lupus lesions followed by two separate rounds of laser treatment on the lesions. The study will take place at the UCF Health clinic on Tavistock Lakes Blvd. and will require three total visits to the clinic. A date and time will be arranged with you. You will receive the treatment for your cutaneous lupus at no cost. If you are interested in participating in this study or would like more information, please contact Dr. David Weinstein (david.weinstein@ucf.edu) or Samantha Prabakaran (sprabakaran@knights.ucf.edu).